A shooter killed one person and injured another near 29th Avenue and Huron Street in the Ballpark section of Five Points on Wednesday before trying to flee to the mountains.
The deceased victim died at the scene, a Denver Police Department spokesman said. The injured victim was taken to the hospital. One victim was a man and one was a woman.
Police received calls about the shooting at 11:42 a.m.
Partnering law enforcement officials have apprehended a suspect driving in Jefferson County to "the mountains" on Highway 285, the spokesman said.
SWAT team officers and officers with the Bureau of Alcohol, Tobacco, Firearms and Explosives were on the scene.